Part Used : ผล
Activity : SLEEP TIME INCREASED
Solvent/Active Compound : saponin
Type of experiment : in vivo
Type of animal : rat
N(Total) : -
N(Treatment) : -
Route : Oral administration
Dose/Conc.(herb) : Sapindus mukorossi saponin fraction 0.2 g/kg
Duration : One time
Type of interaction : Pharmacodynamics
Interaction with drug : Pentobarbital*/Pentobarbitone
Dose/Conc.(drug) : -
Remark : Oral dose of Sapindus mukorossi saponin fraction 0.2 g/kg, significantly increases the pentobarbitone sleep time when compared to the control, indicating the cytochrome P450 inhibition activity.